We like this show lots! Thus, our continuing coverage:
The oft-overlooked actual difficulties of space settlement. Not technology and logistics, but like, how hard it will likely be for the humans doing the job at first. And second. And then for a while after, too.
Growing fresh food in space habitats. Poop-potatoes. Wide-spectrum LEDs. Self-contained hydroponics/aeroponics.
Turning people into jelly. Differing human sensitivity to sustained g-forces in different directions. The wonderful engineering concept of the ship with omnidirectional seating that reconfigures on-the-fly for optimal g-resistance (The Razorback).
Turning into jelly and then having your jelly explode your ship, because physics. Relativistic baseballs. Long-haul space-racing and how to be your own butt-wiping pit crew.
Nuclear non-proliferation treaties in space. Orbital kinetic weapons and cloaked nuke-ships playing the role of the submarine as deterrent.
Minimum viable star system bootstrap answering machine. The Fermi paradox. The odds that most of the signs of alien civilization that we might discover would be past.